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Multi Biotic Dental Drops

Multi Biotic Dental Drops

A clinically validated trio of oral probiotics that are native to a healthy mouth shown to improve overall oral health, freshen breath and boost your mouth's natural defenses. Multi Biotic is suspended in organic MCT oil with vitamin D3 and natural mint flavor. To be used nightly after brushing, these drops work topically overnight to help shift the oral ecosystem to balance. A first in oral care. 

Oral Probiotic
Clinically Studied
Dentist Formulated
Free delivery from $40
30-day returns
Clinically studied
3 live probiotic strains
Targets bad, protects good
Clean-certified 

How to use

Use nightly after brushing, place drops on your tongue and move around your mouth to create a nice even coat. Dosing is such that you shouldn't need to spit excess. Let the triple-strain probiotics modulate your oral microbiome while you sleep.

When you'll notice it

Multi Biotic Drops works gradually, because it's rebalancing an ecosystem rather than masking a symptom. Most people notice a fresher, cleaner-feeling mouth in the first couple of weeks. The strain colonizes over the first month, and the fuller shift toward a balanced microbiome builds over roughly eight weeks of consistent use. Consistency matters more than intensity, which is why most people start on the 3-month supply.

What's in it, what's not

In: Three clinical proven strains of live probiotics and vitamin D3 suspended in organic MCT oil with a hint of natural mint flavoring.

Not in: harsh additives that strip the good bacteria along with the bad. Vegan, and safe to swallow.

How the subscription works

Your first order ships in full. After that, refills arrive automatically on the cadence you choose, so you never run out mid-routine, which is when most people lose the progress they've built. Pause, skip, reschedule or cancel anytime from your account. No lock-in, no fees.

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Oral care spent 100 years killing bacteria.
Your mouth needs the opposite.

We don't kill the microbiome. We optimize it, with S. Dentisani 7746, made to work for you. Good bacteria protect your mouth. We help them win. Balance is the point. It's even in the name.

Your mouth is a microbiome, the second-largest in your body. Conventional toothpaste strips the good bacteria along with the bad. When you sterilize your mouth the bad bacteria colonizes more quickly than the good creating dysbiosis.

Imbalance is the real problem, most oral health problems (cavities, bad breath, inflammation, etc) begin when that ecosystem falls out of balance.

Backed by clinical research on the probiotic strains in our formula (Nart et al., Journal of Clinical and Experimental Dentistry, 2021), shown to colonise the mouth and support a balanced oral microbiome.

Multi Biotic.
Three benefits, every night.

Restores beneficial bacteria

Three live oral probiotic strains help replenish beneficial bacteria while you sleep.

Supports microbiome balance

Supports a balanced oral microbiome throughout the night after brushing.

Supports natural defenses

Vitamin D3 helps support your mouth's natural protective functions.

"Brushing is only half the story. Your mouth keeps changing overnight, so we made drops for it."

— [Founder name], Founder, Duo Biotic

Leading clinically studied probiotic strains working together overnight.

Research-backed probiotic strains selected to support a balanced oral microbiome while you sleep.

Balanced
oral microbiome

supports beneficial bacteria

Fresher breath

overnight support

Healthier
oral ecosystem

works while you sleep

Natural
oral defenses

powered by Vitamin D3

The only dental drops that restore your microbiome overnight.

No conventional oral care product supports your microbiome like this.

Others
"Natural"
Restores beneficial bacteria
Three live probiotic strains
Rare
Clinically studied probiotics
Rare
Works overnight
Vitamin D3
Some

Guided by the people who define the field.

Top researchers, dentists and doctors from the world’s leading oral health research institutions.

Dr. Eve Lofthus

Dr. Eve Lofthus

Board Certified Dentist

Evenmouth Founder

Prof. Hatice Hasturk, DDS

Prof. Hatice Hasturk, DDS

Director of Oral Research

ADA Forsyth Institute

Dr. Alex Mira

Dr. Alex Mira

Oral Microbiome Researcher

Fisabio

Dr. Thomas Van Dyke

Dr. Thomas Van Dyke

VP of Clinical Research

ADA Forsyth Institute

Dr. Brett Kessler

Dr. Brett Kessler

2025 ADA President

Oral Microbiome Advocate

Dr. Aruna Rao, DDS, MS

Dr. Aruna Rao, DDS, MS

VP Minnesota Dental Association

Private practice pediatrics

Dr. Diana Thiara, MD, MS

Dr. Diana Thiara, MD, MS

Longevity Medicine

Associate Professor, UCSF

Dr. Avo Samuelian

Dr. Avo Samuelian

Doctor, Gotham Dental

Member, ADA, AGD & NY 1st District Dental Society

Anne O. Rice, RDH

Anne O. Rice, RDH

Oral Health Educator, Advocate

Author, Member & Lecturer ADHA

Dr. Mira's research team

Valencia, Spain

Every ingredient has a job.

Three research-backed ingredients, each supporting your oral microbiome overnight.
No artificial flavors, preservatives or unnecessary additives.

Three clinically studied live probiotic strains selected to replenish beneficial bacteria and support a balanced oral microbiome while you sleep.

Benefits

  • Supports a balanced oral microbiome
  • Replenishes beneficial bacteria
  • Works overnight while you sleep

Plant-based vitamin D3, sourced from lichen. It helps your body absorb calcium, the mineral that keeps teeth strong and gums healthy, so the rest of the formula has something solid to work with.

Benefits

  • Supports calcium absorption for stronger teeth
  • Helps keep gums healthy
  • Plant-based and vegan-friendly

A clean, coconut-derived base that carries every active ingredient where it needs to go. It also brings its own gentle antimicrobial support to help keep your mouth fresh overnight.

Benefits

  • Naturally supports a cleaner, fresher mouth
  • Acts as a gentle carrier for the actives
  • Sourced from organic coconut

Caprylic/Capric Triglyceride (organic), Flavor, Cholecalciferol (from Barbata (Lichen) Extract), Lactobacillus brevis, Pediococcus acidilactici. Lactiplantibacillus plantarum

We're serious about facts. Ask away.

Unlike traditional oral care that removes both good and bad bacteria, Multi Biotic Dental Drops help replenish beneficial bacteria overnight to support a healthier oral microbiome.

It's a specific oral strain, delivered where it colonizes. A gut probiotic won't survive or settle in your mouth. Different bacteria colonize in different environments.

The microbiome science in Multi Biotic Dental Drops is relatively new and exciting! It's a breakthrough in oral health.

The triple-strain probiotics go to work right away to start helping to balance your oral microbiome to a healthier state. If using overnight, you'll start noticing a different feeling in your mouth when you wake up in the morning. After extended use don't be surprised by affirmation at your next dental check up.

Support your microbiome. While you sleep.

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